CD4-Positive T Cell-Mediated Neuroprotection Requires Dual Compartment Antigen Presentation
نویسندگان
چکیده
منابع مشابه
CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation.
Our laboratory discovered that CD4-positive (CD4+) T cells of the immune system convey transitory neuroprotection to injured mouse facial motoneurons (FMNs) (Serpe et al., 1999, 2000, 2003). A fundamental question in the mechanisms responsible for neuroprotection concerns the identity of the cell(s) that serves as the antigen-presenting cell (APC) to activate the CD4+ T cells. Here, we first es...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2004
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5276-03.2004